General Cell Lines and Cell Cultures
Biochain Institute Inc Frozen Tissue Section - Arteriosclerosis Artery and Matched Non-arteriosclerosis Artery, 2 x 5 slides/PK
BioChain's tissue products are based on the sample repository network established following the IRB-approved ethical standard and procedures. The tissues are immediately put in liquid nitrogen after being excised, and then identified by a board-licensed pathologist. Patient demographic and disease related history data are available. BioChain's frozen tissue section line encompasses a large selection of tissue sections which are good for immunohistochemistry and in situ hybridization. The tissue sections are approximately 5-10 um thick.
ATCC Saccharomyces cerevisiae
An ampoule containing viable cells (may include spores and mycelia) suspended in cryoprotectant.
ATCC Quantitative Genomic DNA from; Campylobacter coli; Strain: CIP 7080
Quantitative genomic DNA from Campylobacter coli strain CIP 7080 can be used for assay development, verification, and validation as well as monitoring of day-to-day test variation and lot-to-lot performance of molecular-based assays. The quantitative format allows for the generation of a standard curve for quantitative PCR (qPCR) to determine bacterial load.
ATCC Escherichia coli; Strain 99-3071
Escherichia coli strain 99-3071 is a whole-genome sequenced strain that was isolated from stool. It is non-toxigenic and is a negative control for STEC virulence genes. This strain is serotype O145:H34.
ATCC Campylobacter upsaliensis; genomic DNA
Genomic DNA isolated from Campylobacter upsaliensis Strain RM3195. This bacterial strain is also available as ATCC Catalog No. BAA-1059™.
Eurofins Discoverx ChemiScreen D5 Dopamine Receptor Stable Cell Line, 2 vials. (HTS129C)
The ChemiScreen D5 Dopamine Receptor Stable Cell Line is an engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. dopamine) based activation of DRD5 GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses DRD5 alongside endogenous high levels of the promiscuous G protein, Gα15, coupling the receptor to the calcium signaling pathway. Upon activation of DRD5, the resulting calcium activity can be fluorescently assayed. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, visit www.discoverx.com/targets/gpcr-target-biology.
Eurofins Discoverx PathHunter U2OS TIM3/TIM3 Dimerization Cell Line, 2 vials. (93-1082C3)
The PathHunter TIM3/TIM3 Dimerization cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting receptor-receptor interaction. This cell line enables assessment of ligand induced dimerization of TIM3/TIM3 receptors. This product uses EFC technology. The cell line included overexpresses TIM3 target protein fused to PK alongside TIM3 target protein fused to EA. Upon ligand-induced dimerization of TIM3/TIM3, detectable EFC signal is produced. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/checkpoint.
Biochain Institute Inc Paraffin Tissue Section - Human Diabetic Diseased Tissue: Parathyroid, 5 slides/PK
BioChain's tissue products are based on the sample repository network established following the IRB-approved ethical standard and procedures. BioChain's formalin fixed paraffin embedded (FFPE) tissue section line encompasses a large selection of tissue sections which are suitable for immunohistochemistry and in situ hybridization assays. The tissue sections are approximately 5 um thick. Each slide contains tissue from single human diseased sample. Documentation of tissues' clinical histories may be available upon request. For those customers who want to perform FFPE DNA and RNA isolation, BioChain can provide tissue section slices in tubes instead of mounting them on glass slides.
Eurofins Discoverx PathHunter CHO-K1 DRD2L (Long Isoform) β-Arrestin Cell Line, 2 vials. (93-0579C2)
The PathHunter DRD2L cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. dopamine) based activation of DRD2L GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged DRD2L and EA-tagged β-Arrestin-2. Activation of DRD2L stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Genscript Corporation CD47 Fc Chimera Human
Leukocyte surface antigen CD47 is also known as Antigenic surface determinant protein OA3 Integrin-associated protein (IAP) and Protein MER6 CD47 contains 1 Ig-like V-type (immunoglobulin-like) domain CD47 is a 40 60 kDa variably glycosylated atypical member of the immunoglobulin superfamily and an integral membrane protein that consists of a 123 amino acid (aa) extracellular domain (ECD) with a single Ig-like domain five membrane-spanning regions with short intervening loops and a 34 aa C-terminal cytoplasmic tail CD47 has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets and in the modulation of integrins and plays an important role in memory formation and synaptic plasticity in the hippocampus by similarity CD47 is the receptor for SIRPA binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells CD47 Interaction with SIRPG mediates cell-cell adhesion enhances superantigen-
Discovery Life Sciences Pancretic Ca Prog/Ref/Rel PBMC
PBMCs Peripheral Blood Mononuclear Cells are immune cells isolated from whole blood and viably cryopreserved providing a foundational material for immunology studies cell therapy research and functional immune assays
Discovery Life Sciences Kidney Ca Act Tx IO PBMC
PBMCs Peripheral Blood Mononuclear Cells are immune cells isolated from whole blood and viably cryopreserved providing a foundational material for immunology studies cell therapy research and functional immune assays
Discovery Life Sciences Leukemia CLL Tx Naive PBMC
PBMCs Peripheral Blood Mononuclear Cells are immune cells isolated from whole blood and viably cryopreserved providing a foundational material for immunology studies cell therapy research and functional immune assays
Discovery Life Sciences CRC Mutation PBMC
PBMCs Peripheral Blood Mononuclear Cells are immune cells isolated from whole blood and viably cryopreserved providing a foundational material for immunology studies cell therapy research and functional immune assays